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درباره این کتاب:
The main focus of this
book entitled is to provide an up-to-date
coverage of marine sponges and their
significance in the current era. This book
is an attempt to compile an outline of
marine sponge research to date, with
specific detail on these bioactive
compounds, and their pharmacological and
biomedical applications.
The book encompasses twenty chapters
covering various topics related to Marine
Sponges. Initial couple of chapters deal
about the worldwide status of marine
sponge research, the recent findings
regarding dynamics of sponges, and several
interesting research areas, that are
believed to be deserving of increased
attention. Variety of sponges, their
toxicology, metagenomics, pharmaceutical
significance and their possible
applications in biomedicine has been
discussed in detail. The second half of
this part includes chapters on chemical
ecology of marine sponges followed by the
discussion on importance of bioeroding
sponges in aquaculture systems. The
following four chapters of the book deal
majorly with the chemical molecules of
marine sponges. In the fifth chapter,
marine sponge-associated actinobacteria
and their pysicochemical properties have
been discussed followed by their bioactive
potential. The biological application of
marine sponges has been presented in later
chapters with the classification of
biologically active compounds being
explored in detail.
The second half of the book presents the
vast repertoire of secondary metabolites
from marine sponges, which include
terpenoids, heterocycles, acetylenic
compounds, steroids and nucleosides.
Further, the bioactive potential of these
compounds has also been discussed. One of
the constituent chapter elaborates the
bioactive alkaloids from marine sponges
namely, pyridoacridine, indole,
isoquinolene, piperidene, quinolizidine,
steroidal and bromotyrosine alkaloids
isolated from them. In the next couple of
chapters, important sponge polymers and
the anticancer effects of marine sponge
compounds have been presented.
The most interesting aspect of sponge
biology is their use in biomedical arena.
An effort has been made in this book, to
cover the major constituents of sponges
and their biomedical potentials. The major
portion of sponge body is composed of
collagen and silica and used in tissue
engineering as scaffold material. This
part of the book compiles chapters
delineating the isolation of sponge
biomaterials including collagen and their
use in medical diagnostics. Overall, this
book would be an important read for novice
and experts in the field of sponge
biology.
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