This manual was written for those interested in establishing an aquaculture operation, with minimal experience in this activity, limited technical support and restricted access to information. It stems directly from one of the author’s experience and differs from other manuals by its precision and amount of detail, going one step further in providing a practical template in the building of a hatchery which can be directly copied or modified if needed. Because it focuses on developing aquaculture in resource-limited areas, the manual has been written with the assumption that the user has little, if any, information sources. For this reason, the manual stands as an entity, providing not only the technicalities of setting up and operating a hatchery, but also makes some of the scientific background, deemed useful to the aquaculturist, readily accessible.